Important info for supplements:
- mechanism of action
- effects
- evidence strong/weak
- frequency
- dosage
- studies and resources
Mineralz
- Omega 3 EPA/DHA: 2.5/1g
- vit D: 5k IU
- deficiency in west has been called a health crisis.
- Peter Atila: targets 40 - 60 ng/ml blood level of 25-hydroxy vitamin
D
- vit K2
- NIH: 120mg for males, 90 mg for females
- https://ods.od.nih.gov/factsheets/VitaminK-HealthProfessional/
- zinc: 15mg
- important for healthy test levels
- NIH guidelines: 11mg for males, 8mg for females. 40 mg upper
limit.
- https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/
- boron: 4mg
- nonessential, good for bones and lowers SHBG
- NIH: safe range 1-13mg
- https://ods.od.nih.gov/factsheets/Boron-HealthProfessional/#h4
Food
- creatine: 5g
- very well studied, very well tolerated, numerous brain and body
health benefits. DYOR
- glutamine: 5g
- amino acid needed during traumetic conditions like injury or
illness.
- may also be an anti-inflammatory agent
Longevity
- NAD+ is the non-patented alternative to NMN/NR.
- Correlated with mitochondrial health, and therefore energy
levels.
- Decreases with aging. No data showing lifespan increases with
supplementing.
- https://www.healthline.com/nutrition/nicotinamide-riboside
Sleep
Take all below 30-60 mins before bed.
- Glycine: 6g
- amazing for sleep. requires a few days before noticeable
effect.
- an essential amino acid, we get 6g from food typically but 12g is
recommended. so take a dose of 3-6g to bump up your levels.
- https://examine.com/supplements/glycine/#dosage-information
- Magnesium threonate: 140mg
- magnesium very important for body in enzymatic reactions
- can activate parasympathetic nervous system, slowing heart and
calming muscles.
- both threonate and glycinate and cross blood brain barrier
- NIH: RDA of 420mg for males, 320 mg for females
- https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/#h2
- Theanine: 100-300mg
- calming effects, increases alpha brain waves
- can be stimulating for some people
- Apigenin: 50mg
- extract from camomile
- not recommended for women since suppresses estrogen
- men should also be cautious since we need estrogen too
- Myo-Inositol: 900mg
- used for cellular signalling and found in foods like citrus, beans
and nuts.
- promising benefits for diabetes/insulin control, and managing high
androigen levels in women.
- improves time to fall asleep and sleep quality:
https://pubmed.ncbi.nlm.nih.gov/32933356/
- studies typically administer 1-4g
- https://examine.com/supplements/inositol/
- GABA: 100mg
- major inhibitory neurotransmitter
- limited studies
- safe and well-tolerated
- does not seem to reach to brain easily
- 100-300mg for sleep, 800mg for improved attention
- https://examine.com/supplements/gaba/
- https://old.reddit.com/r/adhdwomen/comments/nr19pv/gaba_supplements/
Test
- Tongkat ali: 400mg
- increases test
- doses from 100mg to 600mg
- take it early for mild stimulant effect
- must be taken every day since it only works after month 2-3
- huberman claims it does not need cycling since it doesn’t lower
natural test. Want to research this claim more first.
- possible contamination by heavy metals in malaysia (check
origin)
- lowers stress
Adaptogen
- Ashwagandha: 600mg
- not before exercise
- dose (250-300) at afternoon and in the evening
- affects HPA axis and lowers cortisol
- cycle this. stop after a few days to prevent dependence and
tolerance. after 30 days max, take 2-4 weeks break.
- Rhodiola Rosea:
- adaptogen that is anti-fatigue
- reduce fatigue, good pre-workout to push harder
- enhance memory and cognition
- The Rhodiola extract should contain 3% rosavins and 1%
salidroside.
- It’s best to take on an empty stomach, but not close to bedtime, due
to its slight stimulant effect.
- In terms of dosage, amounts as low as 50 mg have been found to
reduce fatigue, with 680 mg being the suggested upper limit, due to a
bell-curve effect.
- lowers fatigue and improves speed for exercise performance.
- considered safe but may have interactions with some drugs so
consider taking it intermittently as needed.
- https://examine.com/supplements/rhodiola-rosea/